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    • Michiel Pegtel
    • Rubina Baglio
    • Esther Drees
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    • Caitrin Crudden
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    • Nils Groenewegen
    • Wendy Onstenk
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Marie Curie postdoctoral fellow

​Research focus

Cancer cell signaling
Molecular mechanisms of exosome biogenesis
Inhibiting extracellular vesicle release as a therapeutic strategy in cancer

 
Curriculum Vitae 
Caitrín Crudden obtained her Masters degree in Cancer Research and Molecular Biomedicine at the University of Manchester (UK), after two research internships delving into the intricacies of cancer cell signaling. In 2014 she started a PhD at Karolinska Institutet (Stockholm, Sweden), developing novel approaches to control plasma membrane receptor (RTK/GPCR) expression and function in cancer, under the supervision of Dr. Leonard Girnita (Department of Oncology-Pathology). With a peaked interest in the central role of the endosome as a portal connecting extra- and intra-cellular signaling, following her PhD defense she joined the Exosome Research Group as a postdoctoral researcher. Here, she will explore the molecular mechanisms surrounding the endosome-to-exosome route, with particular focus on identifying therapeutic intervention opportunities. Her current project, funded by a KWF grant, aims to identify drugs to inhibit extracellular vesicle release to combat drug resistance in breast cancer.

  • Home
  • RESEARCH
    • Pegtel's lab >
      • Tumor exosome biology
      • EV RNA biology
    • Baglio's lab >
      • EV-mediated communication in the tumor microenvironment
  • Team and staff
    • Michiel Pegtel
    • Rubina Baglio
    • Esther Drees
    • Maarten Bebelman
    • Caitrin Crudden
    • Monique van Eijndhoven
    • Nils Groenewegen
    • Wendy Onstenk
  • Publications
  • Media
    • Bill & Melinda Gates Foundation
    • Trouw
    • NRC
    • KWF
  • Vacancies
  • Contact