Drees EE, Driessen J, Zwezerijnen GJC, Verkuijlen SAWM, Eertink JJ, van Eijndhoven MAJ, Groenewegen NJ, Vallés-Martí A, de Jong D, Boellaard R, de Vet HCW, Pegtel DM, Zijlstra JM. Blood-circulating EV-miRNAs, serum TARC, and quantitative FDG-PET features in classical Hodgkin lymphoma. eJHaem. 2022 April.
Drees EE, Roemer MGM, Groenewegen NJ, Perez-Boza J, van Eijndhoven MAJ, Prins LI, Verkuijlen SAWM, Tran X-M, Driessen J, Zwezerijnen GJC, Stathi P, Mol K, Karregat JJP, Kalantidou A, Vallés-Martí A, Molenaar TJ, Aparicio-Puerta E, van Dijk E, Bauke Y, Groothuis-Oudshoorn CGM, Hackenberg M, de Jong D, Zijlstra M, Pegtel DM. Extracellular vesicle miRNA predict FDG-PET status in patients with classical Hodgkin Lymphoma. Journal of extracellular vesicles. 2021 Jul.
Meulenbelt I. Ramos YFM, Baglio SR, Pegtel DM. Censoring exosomal crosstalk in osteoarthritis. Nature aging. 2021 Apr.
Bebelman MP, Janssen E, Pegtel DM, Crudden C. The forces driving cancer extracellular vesicle secretion. Neoplasia. 2021 Jan.
Bebelman MP, Crudden C, Pegtel DM, Smith MJ. The convergence of Extracellular Vesicle and GPCR Biology. Trends in Pharmacological Sciences. 2020 Sep
Bebelman MP, Smit MJ, Pegtel DM, Baglio SR. Biogenesis and function of extracellular vesicles in cancer. Pharmacol Ther. 2018 Feb 21.
Verweij FJ, Bebelman MP, Jimenez CR, Garcia-Vallejo JJ, Janssen H, Neefjes J, Knol JC, de Goeij-de Haas R, Piersma SR, Baglio SR, Verhage M, Middeldorp JM, Zomer A, van Rheenen J, Coppolino MG, Hurbain I, Raposo G, Smit MJ, Toonen RFG, van Niel G, Pegtel DM. Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling. J Cell Biol. 2018 Jan 16.
Baglio SR, Lagerweij T, Pérez Lanzón M, Xuan Ho D, Léveillé N, Melo SA, Cleton-Jansen AM, Jordanova ES, Roncuzzi L, Greco M, van Eijndhoven MA, Grisendi G, Dominici M, Bonafede R, Lougheed S, de Gruijl TD, Zini N, Cervo S, Steffan A, Canzonieri V, Martson A, Maasalu K, Koks S, Wurdinger T, Baldini N, Pegtel DM. Blocking tumor-educated MSC paracrine activity halts osteosarcoma progression. Clinical Cancer Research. 2017 Jan 4.
van Eijndhoven MA, Zijlstra JM, Groenewegen NJ, Drees EE, van Niele S, Baglio SR, Koppers-Lalic D, van der Voorn H, Libregts SF, Wauben MH, de Menezes RX, van Weering JR, Nieuwland R, Visser L, van den Berg A, de Jong D, Pegtel DM. Plasma vesicle miRNAs for therapy response monitoring in Hodgkin lymphoma patients. JCI Insight. 2016 Nov 17.
Baglio SR, van Eijndhoven MA, Koppers-Lalic D, Berenguer J, Lougheed SM, Gibbs S, Léveillé N, Rinkel RN, Hopmans ES, Swaminathan S, Verkuijlen SA, Scheffer GL, van Kuppeveld FJ, de Gruijl TD, Bultink IE, Jordanova ES, Hackenberg M, Piersma SR, Knol JC, Voskuyl AE, Wurdinger T, Jiménez CR, Middeldorp JM, Pegtel DM. Sensing of latent EBV infection through exosomal transfer of 5'pppRNA. Proc Natl Acad Sci USA. 2016 Jan 14.
Zomer A, Maynard C, Verweij FJ, Kamermans A, Schäfer R, Beerling E, Schiffelers RM, de Wit E, Berenguer J, Ellenbroek SI, Wurdinger T, Pegtel DM, van Rheenen J. In Vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior. Cell. 2015 May 21;161(5):1046-57.
Baglio SR, Rooijers K, Koppers-Lalic D, Verweij FJ, Pérez Lanzón M, Zini N, Naaijkens B, Perut F, Niessen HW, Baldini N, Pegtel DM. Human bone marrow- and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive miRNA and tRNA species. Stem Cell Res Ther. 2015 Jul 1;6:127.
Koppers-Lalic D, Hackenberg M, Bijnsdorp IV, van Eijndhoven MAJ, Sadek P, Sie D, Zini N, Middeldorp JM, Ylstra B, de Menezes RX, Wurdinger T, Meijer GA, and Pegtel DM. Nontemplated nucleotide additions distinguish the small RNA composition in cells from exosomes. Cell Rep. 2014;8(6):1649–58.
Koppers-Lalic D, Hogenboom MM, Middeldorp JM, Pegtel DM. Virus-modified exosomes for targeted RNA delivery; a new approach in nanomedicine. Adv Drug Deliv Rev. 2013 Mar;65(3):348-56.
Verweij FJ, van Eijndhoven MA, Hopmans ES, Vendrig T, Wurdinger T, Cahir-McFarland E, Kieff E, Geerts D, van der Kant R, Neefjes J, Middeldorp JM, Pegtel DM. LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activation. EMBO Journal 2011; 30: 2115-2129
Pegtel DM, Cosmopoulos K, Thorley-Lawson DA, van Eijndhoven MA, Hopmans ES, et al. Functional delivery of viral miRNAs via exosomes. Proc Natl Acad Sci USA. 2010;107:6328-6333.
Pegtel DM, Subramanian A, Tzun-Shiahn Sheen. Tsai CH, Golub TR, Merit D, Thorley-Lawson DA. Interferon stimulated genes and EBV Gene Expression distinguish WHO type II and III Nasopharyngeal Carcinoma. Cancer Research. 2007; 67:474-8